Skip to main content

Awareness Capital

Advancing the Next Generation of Brain & Mental Health Companies

We invest in scalable, AI-enabled companies translating breakthrough science into diagnostics, therapeutics, and care delivery.

Mission

Brain and mental health shapes how people live, learn, work, and connect.

Awareness Capital backs serious founders translating credible science into practical care, better diagnostics, and stronger support systems. We care about long-horizon outcomes, but we start with what can make life better now.

Brain Health McKinsey estimates brain health represents a $1 trillion+ addressable market—larger than cardiovascular or oncology—yet it receives a fraction of the R&D investment.

The scale of the problem still outweighs the flow of capital.

Brain and mental health has long been underfunded relative to its global impact. That dynamic is now changing. Advances in AI, data science, biomarkers, and precision medicine are enabling new approaches to diagnosis, treatment, and care delivery—creating a period of accelerated innovation.

1 in 3+ People affected

by brain & mental health conditions across the lifespan

$6T Projected annual

cost by 2030

2% <5% VC firms active

in brain & mental health

Approach

We focus where strong science, early traction, and disciplined execution meet.

Our investment thesis is centered on scalable, AI-enabled companies in brain and mental health—where clinical validation and commercial readiness intersect.

Mid-Stage Focus

We invest in companies with early traction and validated models—reducing early-stage risk while preserving exposure to high-growth outcomes.

AI-Enabled & Science-Led

We back companies applying AI, data, and advanced science across therapeutics, diagnostics, and care delivery—unlocking new approaches to brain and mental health.

Ecosystem-Driven Platform

Our network across science, healthcare systems, and mission-aligned organizations enables differentiated access, rigorous diligence, and accelerated company scaling.

Diligence

Network-driven, evidence-led, and capital efficient.

We invest through domain expertise, deeper networks in brain health, scientific and clinical rigor, and a capital-efficient approach.

1

Specialist network

Our network across brain & mental health – clinicians, founders, and advisors – helps us see strong opportunities early.

2

Scientific & clinical vetting

We evaluate scientific validity, clinical relevance, and feasibility with support from a world-class advisory network.

3

Capital-efficient selection

We focus on businesses that can reach meaningful scale without unusually capital-intensive development.

4

High-conviction partnership

When we invest, we support companies with practical guidance, relevant introductions, and help accessing global markets.

Why Us

A Differentiated, Global Platform

Awareness Capital operates at the intersection of science, care delivery, and venture capital—supported by a network of leading researchers, clinicians, and mission-aligned organizations.

Ecosystem Deal Flow

Access to opportunities emerging from relationships across academia, non-profits, and operators—including organizations such as One Mind.

Scientific & Clinical Depth

Investment decisions informed by domain experts, advisors, and ongoing engagement with the research community.

Pathways to Adoption

Connections to healthcare systems, providers, and commercialization channels that support early traction and scale.

Global Reach

Bridging UK and European innovation with U.S. capital, regulatory pathways, and market access.

Aligned Ecosystem Model

A portion of GP carry is committed to supporting mission-aligned non-profit organizations—reinforcing the ecosystem that drives innovation, talent, and company formation.

Portfolio

Companies translating brain-health science into care.

From early-stage diagnostics to scaled care delivery — a horizontal slice of the companies in our active portfolio.

Team

Operators, scientists, and investors working from the same thesis.

We combine venture experience, translational judgment, and a long-term commitment to better brain and mental health outcomes.

Team

Gwill York

Gwill York

General Partner

Founding Managing Director, Lighthouse Capital Partners; Director, One Mind; Chair, Board of Fellows, Harvard Medical School. MBA, Harvard Business School; AB Economics, Harvard.

LinkedIn
Dr Joshua Chauvin

Dr Joshua Chauvin

Venture Partner

Entrepreneur and cognitive neuropsychologist with two decades experience in global mental health. Has led and advised digital health startups, with deep expertise in scaling evidence-based interventions and building cross-sector partnerships. Rhodes Scholar, University of Oxford.

LinkedIn
Charles Finnie

Charles Finnie

General Partner

Veteran investor in enterprise software and AI. Led early bets in C3.ai, Ask Jeeves, Kana, and Macromedia. Brings deep pattern recognition across platform technology cycles to the brain health category.

LinkedIn
Garen Staglin

Garen Staglin

General Partner (Fund I) & Advisor

Philanthropist-investor who co-founded ONE MIND and served as a partner in Awareness Fund I. Has spent decades advancing mental-health research, reducing stigma, and building the infrastructure for brain-health innovation.

LinkedIn
Kathy Guerry

Kathy Guerry

CFO

Seasoned financial executive with 30+ years supporting entrepreneurial companies and investment funds. Brings hands-on CFO leadership across venture capital fund accounting, investor relations, and financial operations.

LinkedIn

Advisors & Network

Dr Michelle Tempest

Dr Michelle Tempest

Psychiatrist & Company Advisor

Industry
Prof. Richard Huganir

Prof. Richard Huganir

Neuroscience Leader

John Hopkins Scientific
Dr Eric Nestler

Dr Eric Nestler

Neuroscience Leader

Mount Sinai Scientific
Prof. Robert Malenka

Prof. Robert Malenka

Psychiatry & Behavioral Sciences

Stanford Scientific
Diana Saville

Diana Saville

Cofounder & President

BrainMind Strategic
Resonance Health Europe

Resonance Health Europe

Advisor Network Partner

Resonance Health Europe
Kokoro

Kokoro

Ecosystem Builder

Kokoro

Questions

Common questions, in plain language.

A few of the most-asked questions from founders and co-investors. The full set lives on the FAQ page.

What is brain health?

Brain health encompasses the full spectrum of neurological and psychiatric conditions — from depression, anxiety, and PTSD to neurodegenerative diseases like Alzheimer's and Parkinson's — as well as the broader goal of optimizing cognitive function and emotional wellbeing across the lifespan. The World Health Organization defines it as the state of brain functioning across cognitive, sensory, social-emotional, behavioral, and motor domains, allowing a person to realize their full potential.

How large is the brain health market?

McKinsey Health Institute estimates a $26 trillion total economic opportunity from addressing brain health globally. The annual economic cost of brain disorders is projected to reach $6 trillion by 2030. The brain health supplements market alone is expected to grow from $12.6 billion in 2025 to over $35 billion by 2035, while the broader mental health technology and services market continues to expand at double-digit rates.

Why is brain health considered underfunded?

Mental and neurological conditions account for roughly 14% of the global disease burden — measured in disability-adjusted life years (DALYs) — yet receive only about 2% of domestic government healthcare funding worldwide. Less than 5% of mental health research funding reaches low- and middle-income countries. This mismatch between burden and investment represents one of the largest funding gaps in all of healthcare, and each dollar invested in scaling mental health interventions has an estimated economic return of $5 to $6.

What percentage of VC firms are active in brain health?

Fewer than 2% of venture capital firms have a dedicated focus on brain health. While mental health venture funding saw a 38% rise in 2024 — reaching $2.7 billion — the majority of that capital comes from generalist healthcare funds making opportunistic bets rather than firms with deep domain expertise in neuroscience and psychiatry. This concentration gap is one of the reasons Awareness Capital was founded.

Get in touch

Building in brain or mental health?

We read every inbound. If your work touches diagnostics, therapeutics, digital health, or AI for brain and mental health — we'd like to hear from you.